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Bone Scan

Sunday, February 9, 2020 | 0 comments

Image result for bone scanWhat is a bone scan?

A nuclear medicine bone scan shows the effects of injury or disease (such as cancer) or infection on the bones. A nuclear medicine bone scan also shows whether there has been any improvement or deterioration in a bone abnormality after treatment.
A radioactive material (radiopharmaceutical) is injected into a vein, attaches to the bones and is detected by a special camera (gamma camera) that takes images or pictures that show how the bones are working.

Why would my doctor refer me to have this procedure?

Nuclear medicine bone scans are carried out for many different reasons.
Bone scans image both the structure and the active cell growth of the bones, so are often used in conjunction with other imaging e.g. X-rays, computed tomography (CT) or magnetic resonance imaging (MRI).
They are often used as a follow-up test when the cause of your pain or symptoms needs to be clarified, for example:
  • to evaluate the source of bone pain; for example, foot or hip pain
  • to evaluate the findings from other diagnostic images or abnormal laboratory results.
Listed below are some common reasons why your doctor may refer you for a bone scan:
  • difficult to find fractures, stress fractures, shin splints
  • osteomyelitis (infection of the bone), cellulitis (infection of the skin) or to assess a response to treatment (e.g. antibiotics) you might be having
  • arthritis, Paget’s disease, fractures from osteoporosis (where bones become fragile and are more likely to break)
  • to assess the presence or spread of cancer in bone, then to follow up on the response to treatment
  • complex regional pain syndrome (CRPS or previously known as reflex sympathetic dystrophy), avascular necrosis, prosthesis loosening or infection.

How do I prepare for a bone scan?

There is no special preparation for a bone scan.
However, it is important to drink normally or more than usual, as the radiopharmaceutical is eliminated from your body in your urine. You should continue to take your usual medications.
You will need to lie still while the images are being taken, so they are not blurred. If you feel you will not be able to stay still for a long period of time, please advise your own doctor or the nuclear medicine staff where you are having the scan.
If you are severely claustrophobic, please advise the department when you make your appointment.
If you are (or think you might be) pregnant, breast-feeding and/or the primary or sole carer for small children, you must inform the doctor who is referring you for the bone scan and also the staff where you are having the bone scan.
Bone scans are generally not carried out on pregnant women.
Women who are breast-feeding and people who are the primary or sole carer for small children might need to make special preparations for after the scan. This will involve stopping breast-feeding and avoiding close contact with young children for a short time. This is due to the small amount of radioactivity your body might release after the scan injection. You should discuss this with your referring doctor or with the nuclear medicine practice where you will be having the test.
The Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) has recommendations about breast-feeding and close contact with children after nuclear medicine tests. For a bone scan, the recommended time for not breast-feeding or having close contact with young children is 1 hour. It might be easiest to breast-feed your baby immediately before the test. You might need a bottle of formula or previously expressed breast milk available. Someone else should care for the baby or any young children for the hour after the injection.

What happens during a bone scan?

There are two parts to a bone scan – an injection of radiopharmaceutical into a vein (sometimes accompanied by ‘early’ imaging) and then ‘delayed’ imaging between 1–4 hours later.

Part 1

You will receive an injection of a small amount of radiopharmaceutical into a vein. Sometimes images are taken with the gamma camera immediately after the injection to look at the blood flow to the area being scanned. These images are referred to as ‘early’ (blood flow or blood pool) imaging. Whether or not you have ‘early’ imaging will depend on why your doctor has requested the scan.

Part 2

After 2–4 hours for adults and 1–3 hours for children, you return to have the ‘delayed’ images. These images show how the bones are working. The reason for the length of time between the injection and the ‘delayed’ images is to give the radiopharmaceutical time to be absorbed into the bones.
Some specific images might need to be taken; that is, single-photon emission computed tomography (SPECT; images taken in 3-D showing the height, width and depth of the part of the body being scanned) or SPECT-CT (a combination of SPECT and CT), which can take slightly longer.
The radiopharmaceutical you receive for the bone scan is eliminated from your body through the urine. For that reason, you should drink plenty of fluids and urinate frequently after the injection. How much fluid will depend on each individual, but you should be well hydrated, and for an adult this could be three to four glasses of water. Your urine will not change colour. Your urine will contain the radioactive material, so it is recommended that you wash your hands well after going to the toilet.
In the case of babies and youngsters in nappies who are having a bone scan, there will be a small amount of radioactivity in the urine and therefore in the child’s nappy. The radioactive material will not affect the child’s skin, but carers should wash the child’s bottom and wash their own hands thoroughly. Cloth nappies need to be washed thoroughly and disposable nappies tied in a plastic bag before binning.

Are there any after effects of a bone scan?

Normally, there are no after effects of a nuclear medicine bone scan.
The radiopharmaceutical used in a bone scan is not known to have any adverse interaction with food or medication you might be taking. You should feel no effect from the injection of radiopharmaceutical. You can carry out normal activities between the injection and the delayed images, and after the scan.
If you are breast-feeding or caring for young children, see the ‘how do I prepare’ section for more information about special precautions you might need to take.

How long does a bone scan take?

There are two parts to a nuclear medicine bone scan. In the first part, you receive an injection into a vein in your arm that usually takes 15–30 minutes. This includes time to explain the procedure and take any ‘early’ images, if required.
In the second part, you return after 1–4 hours to have ‘delayed’ images taken. These can take between 15 and 60 minutes, depending on the area/s of interest and any specific images that that have been requested; for example, SPECT or SPECT-CT. Occasionally, the doctor will ask the patient to return for delayed images the next day, particularly if there is a need to see the hips or pelvis in patients who are unable to completely empty their bladder.

What are the risks of a bone scan?

There are minimal risks involved in the nuclear medicine bone scan procedure.
The scan involves a small dose of radiation from the radiopharmaceutical injected into your vein. See Radiation Risk of Medical Imaging for Adults and Children. The dose is similar to CT and fluoroscopy procedures.
If you are breast-feeding or caring for young children, see the ‘how do I prepare’ section for more information about special precautions you might need to take.
Rarely, allergic reactions have been associated with bone scan agents.

What are the benefits of a bone scan?

A bone scan helps your doctor evaluate how your bones are working, and provides information to help diagnose and treat your condition. It can show injury to the bones, the effects of disease such as cancer or infection, as well as any improvement or deterioration in a bone abnormality after any treatment you might be having.

Who does the bone scan?

The nuclear medicine bone scan is carried out by nuclear medicine technologists. The images taken by the technologist are reviewed by a nuclear medicine specialist doctor who provides a written report to the doctor who referred you for the bone scan.

Where is a bone scan done?

Most large public and private hospitals, and private radiology practices have nuclear medicine facilities where bone scans are carried out.

When can I expect the results of my bone scan?

The time that it takes your doctor to receive a written report on the test or procedure you have had will vary, depending on:
  • the urgency with which the result is needed;
  • the complexity of the examination;
  • whether more information is needed from your doctor before the examination can be interpreted by the nuclear medicine specialist;
  • whether you have had previous X-rays or other medical imaging procedures that need to be compared with this new test or procedure (this is commonly the case if you have a disease or condition that is being followed to assess your progress);
  • how the report is conveyed from the practice or hospital to your doctor (i.e. phone, email, fax or mail).
Please feel free to ask the private practice, clinic or hospital where you are having your test or procedure when your doctor is likely to have the written report.
It is important that you discuss the results with the doctor who referred you, either in person or on the telephone, so that they can explain what the results mean for you.

Cardiac PET/CT Scan

Saturday, February 8, 2020 | 0 comments

CARDIAC PET/CT SCAN

Cardiac Positron Emission Tomography (PET)
 exams help to evaluate heart health by
 measuring the blood flow brought by the
coronary arteries to the heart muscle. A small
amount of radiopharmaceutical will be given
through an IV line. This lets the PET scanner
capture pictures of your heart.
Preparing for the test:
  • No caffeine for 24 hours prior to the test such as coffee, tea, soft drinks and chocolate. Do not consume decaffeinated/caffeine free beverages as they contain some residual caffeine.
  • Nothing to eat 6 hours prior to your test. Nothing to drink 4 hours prior to your test.
  • Medications can be taken with a sip of water.
  • If you have diabetes and take insulin, check with you your doctor.
  • Do not take Excedrin or over-the-counter meds, which contain caffeine or decongestants.
  • Avoid tobacco use for 12 hours before the PET scan
  • If you take herbal supplements or stimulants, stop taking them for 72 hours before the PET scan. These include Methylphenidate, Adderall, Vyvanse and Dextroamphetamine,
  • Wear comfortable, loose-fitting clothing.
  • Do not wear jewelry or any metal objects
During the test:
  • The test takes approximately 1 hour
  • You’ll lie on a flat table that’s connected to the PET scanner, (shaped like a giant doughnut)                             to take images of the heart. Two sets of images are taken.
Rest Images:
  • The technician will hook on you ECG electrodes to keep track of your heartbeat during                                  the test and signal the computer when to take a scan.
  • Radioactive tracer will be injected into an IV in your arm and images of the heart                                            will be acquired.
Stress Images:
  • The stress medicine is lexiscan or adenosine. Side effects include headache, dizziness,                               and chest pain, shortness of breath or nausea /abdominal discomfort which are mild                                      and are usually gone in less than 5 minutes.
  • After the stress, we will inject a second dose of the tracer into your bloodstream through                                the IV, another set of pictures of the blood flow to your heart is obtained.
* The amount of radiation you will receive is relatively low. None of these low dose levels are                         associated with increased levels of cancer or other adverse effects.
* Cardiac PET is generally safe as the amount of radiation is small, and your body will get rid                                          of it through your kidneys within about 24 hours. If you’re pregnant or think you might be                                  pregnant, or if you’re a nursing mother, please let us know beforehand as the test could                                         harm your baby.
After the scan:
  • You can usually go back to your normal activities right away
  • Make an appointment with your doctor to discuss the results of the test and next steps

Treadmill Stress Test

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TREADMILL STRESS TEST

The treadmill stress test records the heart’s electrical activity, including rate and rhythm, during
exercise, most often for the diagnosis of coronary artery disease. Exercise places stress on the
heart, and performing a treadmill stress test can bring out abnormalities caused by partial blockages
 in the coronary arteries – abnormalities that may not be apparent at rest.
Preparing for the test:
  • You can drink water, but do not eat anything 4 hours prior to the test
  • Please wear loose, comfortable clothing and comfortable walking shoes
  • Do not put on any lotions on the day of the test
  • Do not consume any caffeine or decaffeinated beverages for 24 hours before your stress test. Items with caffeine include sodas, ‘caffeine free’ sodas, coffee, decaf coffee, tea, decaf tea, chocolate, Excedrin, and certain cold or diet pills
  • If you are diabetic, hold your medication
  • Continue to take all medications except for beta blockers and diabetic medications
  • Bring a snack and drink, if you desire
  • Bring your inhaler(s), if you use them
  • Bring a list of medications and dosages
During the test:
  • We will place electrodes on your chest
  • You will be asked to perform a “graded” exercise test on a treadmill. The exercise-protocol that you will follow will be determined by the cardiologist supervising your test, but will begin at a relatively easy level and become progressively more difficult with each subsequent stage
  • Your blood pressure, heart rate, and ECG will be recorded at frequent intervals at rest and during exercise and after exercise. The physician or technologist may stop the test at any time for medical reasons, and you may ask to stop the test at any time due to fatigue or discomfort. However, we encourage you to exercise as long as possible so that we may assess your heart under maximum stress.

Nuclear Stress Test

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NUCLEAR STRESS TEST

A nuclear stress test measures blood flow to the heart muscle both at rest and when the heart is
under stress, or while exercising. Though it is similar to a routine exercise stress test, it also
provides images that can show areas of low blood flow through the heart and areas of damaged
heart muscle.
If unable to exercise on a treadmill or if requested by your physician for specific circumstances, a
nuclear stress test can also be provided using a pharmacological form of stress that does not
require any physical exertion such as Lexiscan or Adenosine.
Preparing for the test:
  • You can drink water, but do not eat anything 4 hours prior to the test
  • Please wear loose, comfortable clothing and comfortable walking shoes
  • Do not wear any shirts with metallic ornaments
  • Do not put on any lotions on the day of the test
  • Do not consume any caffeine or decaffeinated beverages for 24 hours before your stress test. Items with caffeine include sodas, ‘caffeine free’ sodas, coffee, decaf coffee, tea, decaf tea, chocolate, Excedrin, and certain cold or diet pills
  • If you are diabetic, hold your medication
  • Bring a snack and drink, if you desire
  • Take all medications except for beta blockers and diabetic medications. Please let us know if you have any questions regarding your medication
During the test:
  • A small intravenous (IV) line will be inserted in a vein in your arm. The IV will allow us to inject Cardiolite or a similar radioactive isotope, into the bloodstream, during the rest part of the exam
  • Approximately 30 minutes to an hour later, we will take pictures of the resting blood flow to your heart using a nuclear camera
  • At peak exercise, we will inject Cardiolite into your bloodstream through the IV. You will walk for 1 minute after the injection. The amount of Cardiolite taken up by the heart muscle is in proportion to the blood flow to it through the coronary arteries. After exercise, we will use the nuclear camera to take pictures of the blood flow to your heart
  • The stress portion will be performed next. We will place electrodes on your chest to record your blood pressure, heart rate, and ECG
  • You will be asked to perform a “graded” exercise test on a treadmill. The first stage of the test will begin with the treadmill at a slow speed and a little uphill inclination. Every three minutes the treadmill increases in speed and elevation. The physician or technician may stop the test at any time for medical reasons or you may stop the test because of significant fatigue or discomfort. In general, however, we encourage you to exercise as long as possible in order to maximally stress the blood flow to your heart

What is Nuclear Medicine?

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Nuclear medicine is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear medicine imaging, in a sense, is "radiology done inside out" or "endoradiology" because it records radiation emitting from within the body rather than radiation that is generated by external sources like X-rays. In addition, nuclear medicine scans differ from radiology as the emphasis is not on imaging anatomy but the function and for such reason, it is called a physiological imaging modality. Single photon emission computed tomography (SPECT) and positron emission tomography (PET) scans are the two most common imaging modalities in nuclear medicine. Diagnostic[edit] In nuclear medicine imaging, radiopharmaceuticals are taken internally, for example, intravenously or orally. Then, external detectors (gamma cameras) capture and form images from the radiation emitted by the radiopharmaceuticals. This process is unlike a diagnostic X-ray, where external radiation is passed through the body to form an image. 3D: SPECT is a 3D tomographic technique that uses gamma camera data from many projections and can be reconstructed in different planes. Positron emission tomography (PET) uses coincidence detection to image functional processes. Nuclear medicine tests differ from most other imaging modalities in that diagnostic tests primarily show the physiological function of the system being investigated as opposed to traditional anatomical imaging such as CT or MRI. Nuclear medicine imaging studies are generally more organ-, tissue- or disease-specific (e.g.: lungs scan, heart scan, bone scan, brain scan, tumor, infection, Parkinson etc.) than those in conventional radiology imaging, which focus on a particular section of the body (e.g.: chest X-ray, abdomen/pelvis CT scan, head CT scan, etc.). In addition, there are nuclear medicine studies that allow imaging of the whole body based on certain cellular receptors or functions. Examples are whole body PET scans or PET/CT scans, gallium scans, indium white blood cell scans, MIBG and octreotide scans. Iodine-123 whole body scan for thyroid cancer evaluation. The study above was performed after the total thyroidectomy and TSH stimulation with thyroid hormone medication withdrawal. The study shows a small residual thyroid tissue in the neck and a mediastinum lesion, consistent with the thyroid cancer metastatic disease. The observable uptakes in the stomach and bladder are normal physiologic findings. While the ability of nuclear metabolism to image disease processes from differences in metabolism is unsurpassed, it is not unique. Certain techniques such as fMRI image tissues (particularly cerebral tissues) by blood flow and thus show metabolism. Also, contrast-enhancement techniques in both CT and MRI show regions of tissue that are handling pharmaceuticals differently, due to an inflammatory process. Diagnostic tests in nuclear medicine exploit the way that the body handles substances differently when there is disease or pathology present. The radionuclide introduced into the body is often chemically bound to a complex that acts characteristically within the body; this is commonly known as a tracer. In the presence of disease, a tracer will often be distributed around the body and/or processed differently. For example, the ligand methylene-diphosphonate (MDP) can be preferentially taken up by bone. By chemically attaching technetium-99m to MDP, radioactivity can be transported and attached to bone via the hydroxyapatite for imaging. Any increased physiological function, such as due to a fracture in the bone, will usually mean increased concentration of the tracer. This often results in the appearance of a "hot spot", which is a focal increase in radio accumulation or a general increase in radio accumulation throughout the physiological system. Some disease processes result in the exclusion of a tracer, resulting in the appearance of a "cold spot". Many tracer complexes have been developed to image or treat many different organs, glands, and physiological processes.